A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: Design, synthesis, and in vitro and in vivo evaluation

Obiamaka Obianyo, Corey P. Causey, Tanesha C. Osborne, Justin E. Jones, Young Ho Lee, Michael R. Stallcup, Paul R. Thompson

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1219-1223
Number of pages5
JournalChemBioChem
Volume11
Issue number9
DOIs
StatePublished - Jun 14 2010
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Organic Chemistry

Keywords

  • Cl-amidine
  • Enzymes
  • Inhibitors
  • Protein arginine methyltransferase
  • Transcription

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