Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy

Christina A. von Roemeling; Thomas R. Caulfield; Laura Marlow; Ilah Bok; Jiang Wen; James L. Miller; Robert Hughes; Lori Hazlehurst; Anthony B. Pinkerton; Derek C. Radisky; Han W. Tun; Yon Son Betty Kim; Amy L. Lane; John A. Copland

doi:10.18632/oncotarget.21545

Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy

Christina A. von Roemeling, Thomas R. Caulfield, Laura Marlow, Ilah Bok, Jiang Wen, James L. Miller, Robert Hughes, Lori Hazlehurst, Anthony B. Pinkerton, Derek C. Radisky, Han W. Tun, Yon Son Betty Kim, Amy L. Lane, John A. Copland

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	3-20
Number of pages	18
Journal	Oncotarget
Volume	9
Issue number	1
DOIs	https://doi.org/10.18632/oncotarget.21545
State	Published - 2018

ASJC Scopus Subject Areas

Oncology

Keywords

Cancer
Drug discovery
High throughput drug screening
Lipid metabolism
Stearoyl CoA desaturase

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10.18632/oncotarget.21545

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von Roemeling, C. A., Caulfield, T. R., Marlow, L., Bok, I., Wen, J., Miller, J. L., Hughes, R., Hazlehurst, L., Pinkerton, A. B., Radisky, D. C., Tun, H. W., Kim, Y. S. B., Lane, A. L., & Copland, J. A. (2018). Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy. Oncotarget, 9(1), 3-20. https://doi.org/10.18632/oncotarget.21545

von Roemeling, CA, Caulfield, TR, Marlow, L, Bok, I, Wen, J, Miller, JL, Hughes, R, Hazlehurst, L, Pinkerton, AB, Radisky, DC, Tun, HW, Kim, YSB, Lane, AL & Copland, JA 2018, 'Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy', Oncotarget, vol. 9, no. 1, pp. 3-20. https://doi.org/10.18632/oncotarget.21545

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author = "\{von Roemeling\}, \{Christina A.\} and Caulfield, \{Thomas R.\} and Laura Marlow and Ilah Bok and Jiang Wen and Miller, \{James L.\} and Robert Hughes and Lori Hazlehurst and Pinkerton, \{Anthony B.\} and Radisky, \{Derek C.\} and Tun, \{Han W.\} and Kim, \{Yon Son Betty\} and Lane, \{Amy L.\} and Copland, \{John A.\}",

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AU - Caulfield, Thomas R.

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AU - Bok, Ilah

AU - Wen, Jiang

AU - Miller, James L.

AU - Hughes, Robert

AU - Hazlehurst, Lori

AU - Pinkerton, Anthony B.

AU - Radisky, Derek C.

AU - Tun, Han W.

AU - Kim, Yon Son Betty

AU - Lane, Amy L.

AU - Copland, John A.

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PY - 2018

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KW - Cancer

KW - Drug discovery

KW - High throughput drug screening

KW - Lipid metabolism

KW - Stearoyl CoA desaturase

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Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy

ASJC Scopus Subject Areas

Keywords

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