Does concurrent pharmacotherapy enhance behavioral interventions for mild cognitive impairment? Evidence from the HABIT program

Zhigang Xie; Dona Locke; Anni Shandera-Ochsner; Hanadi Hamadi; Liselotte De Wit; Octavio Santos; Elizabeth A. Boots; Stephanie Aghamoosa; Jeremy Grant; Glenn Smith; Melanie Chandler

doi:10.1177/13872877261471921

Does concurrent pharmacotherapy enhance behavioral interventions for mild cognitive impairment? Evidence from the HABIT program

Zhigang Xie
, Dona Locke
, Anni Shandera-Ochsner
, Hanadi Hamadi
, Liselotte De Wit
, Octavio Santos
, Elizabeth A. Boots
, Stephanie Aghamoosa
, Jeremy Grant
, Glenn Smith
, Melanie Chandler

Public Health

University of Florida
Emory University School of Medicine
Mayo Clinic
Ohio State University
Center for the Science of Health Care Delivery

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	959-968
Number of pages	10
Journal	Journal of Alzheimer's Disease
Volume	113
Issue number	2
DOIs	https://doi.org/10.1177/13872877261471921
State	Published - Sep 2026

ASJC Scopus Subject Areas

General Neuroscience
Clinical Psychology
Geriatrics and Gerontology
Psychiatry and Mental health

Keywords

Alzheimer's disease
clinical outcome
mild cognitive impairment
multicomponent behavioral intervention
pharmacological therapies

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10.1177/13872877261471921

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Xie, Z., Locke, D., Shandera-Ochsner, A., Hamadi, H., De Wit, L., Santos, O., Boots, E. A., Aghamoosa, S., Grant, J., Smith, G., & Chandler, M. (2026). Does concurrent pharmacotherapy enhance behavioral interventions for mild cognitive impairment? Evidence from the HABIT program. Journal of Alzheimer's Disease, 113(2), 959-968. https://doi.org/10.1177/13872877261471921

Xie, Z, Locke, D, Shandera-Ochsner, A, Hamadi, H, De Wit, L, Santos, O, Boots, EA, Aghamoosa, S, Grant, J, Smith, G & Chandler, M 2026, 'Does concurrent pharmacotherapy enhance behavioral interventions for mild cognitive impairment? Evidence from the HABIT program', Journal of Alzheimer's Disease, vol. 113, no. 2, pp. 959-968. https://doi.org/10.1177/13872877261471921

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author = "Zhigang Xie and Dona Locke and Anni Shandera-Ochsner and Hanadi Hamadi and \{De Wit\}, Liselotte and Octavio Santos and Boots, \{Elizabeth A.\} and Stephanie Aghamoosa and Jeremy Grant and Glenn Smith and Melanie Chandler",

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AU - De Wit, Liselotte

AU - Santos, Octavio

AU - Boots, Elizabeth A.

AU - Aghamoosa, Stephanie

AU - Grant, Jeremy

AU - Smith, Glenn

AU - Chandler, Melanie

N1 - Publisher Copyright: © The Author(s) 2026

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KW - Alzheimer's disease

KW - clinical outcome

KW - mild cognitive impairment

KW - multicomponent behavioral intervention

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Does concurrent pharmacotherapy enhance behavioral interventions for mild cognitive impairment? Evidence from the HABIT program

ASJC Scopus Subject Areas

Keywords

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