TY - JOUR
T1 - Leisure-time Aerobic Physical Activity and the Risk of Diabetes-related Mortality
T2 - An Analysis of Effect Modification by Race-ethnicity
AU - Boyer, William R.
AU - Ehrlich, Samantha F.
AU - Crouter, Scott E.
AU - Churilla, James R.
AU - Fitzhugh, Eugene C.
N1 - Boyer, W. R., Ehrlich, S.F., Crouter, S.E., Churilla, J.R., Fitzhugh, E. C. (2021) Leisure-time aerobic physical activity and the risk of diabetes-related mortality: An analysis of effect modification by race-ethnicity. Journal of Diabetes and its Complications, 35(1), 107763. 10.1016/j.jdiacomp.2020.107763
PY - 2021/1
Y1 - 2021/1
N2 - Aims: To examine the relationship between aerobic moderate-to-vigorous intensity leisure-time physical activity (LTPA) and the risk of diabetes-related mortality in the NHANES III (1988–1994) while considering potential effect modification by race-ethnicity. Methods: The study sample (n = 14,006) included adults, 20–79 years of age, with Mobile Examination Center (MEC) data. An age-standardized physical activity score (PAS) was calculated from the self-reported frequency and intensity of 12 leisure-time aerobic activities. Three categories of PA were examined: inactive (PAS = 0), insufficiently active (PAS >0–<10), and active (PAS ≥10). Diabetes-related mortality was defined as death from diabetes mellitus. Cox Proportional Hazard models were used all analyses. Results: A statistically significant reduction in risk was found for insufficiently active (HR 0.59, 95% CI 0.40–0.90) and active non-Hispanic black (NHB) (HR 0.54, 95% CI 0.34–0.88). Among active non-Hispanic white (NHW), a similar pattern of risk reduction was found, however, this relationship was borderline significance (HR 0.59, 95% CI 0.35–1.02, p = 0.06). Conclusions: Any volume of aerobic LTPA is beneficial in terms of reducing the risk of diabetes-related mortality. However, these benefits may differ by racial-ethnic group, with further research on health disparities in the area of PA being warranted.
AB - Aims: To examine the relationship between aerobic moderate-to-vigorous intensity leisure-time physical activity (LTPA) and the risk of diabetes-related mortality in the NHANES III (1988–1994) while considering potential effect modification by race-ethnicity. Methods: The study sample (n = 14,006) included adults, 20–79 years of age, with Mobile Examination Center (MEC) data. An age-standardized physical activity score (PAS) was calculated from the self-reported frequency and intensity of 12 leisure-time aerobic activities. Three categories of PA were examined: inactive (PAS = 0), insufficiently active (PAS >0–<10), and active (PAS ≥10). Diabetes-related mortality was defined as death from diabetes mellitus. Cox Proportional Hazard models were used all analyses. Results: A statistically significant reduction in risk was found for insufficiently active (HR 0.59, 95% CI 0.40–0.90) and active non-Hispanic black (NHB) (HR 0.54, 95% CI 0.34–0.88). Among active non-Hispanic white (NHW), a similar pattern of risk reduction was found, however, this relationship was borderline significance (HR 0.59, 95% CI 0.35–1.02, p = 0.06). Conclusions: Any volume of aerobic LTPA is beneficial in terms of reducing the risk of diabetes-related mortality. However, these benefits may differ by racial-ethnic group, with further research on health disparities in the area of PA being warranted.
UR - https://doi.org/10.1016/j.jdiacomp.2020.107763
U2 - 10.1016/j.jdiacomp.2020.107763
DO - 10.1016/j.jdiacomp.2020.107763
M3 - Article
SN - 1056-8727
VL - 35
JO - Journal of Diabetes and its Complications
JF - Journal of Diabetes and its Complications
IS - 1
M1 - 107763
ER -