Novel fluorinated curcuminoids and their pyrazole and isoxazole derivatives: Synthesis, structural studies, Computational/Docking and in-vitro bioassay

Kenneth K. Laali; William J. Greves; Sebastian J. Correa-Smits; Angela T. Zwarycz; Scott D. Bunge; Gabriela L. Borosky; Alak Manna; Aneel Paulus; Asher Chanan-Khan

doi:10.1016/j.jfluchem.2017.11.013

Novel fluorinated curcuminoids and their pyrazole and isoxazole derivatives: Synthesis, structural studies, Computational/Docking and in-vitro bioassay

Kenneth K. Laali
, William J. Greves
, Sebastian J. Correa-Smits
, Angela T. Zwarycz
, Scott D. Bunge
, Gabriela L. Borosky
, Alak Manna
, Aneel Paulus
, Asher Chanan-Khan

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	82-98
Number of pages	17
Journal	Journal of Fluorine Chemistry
Volume	206
DOIs	https://doi.org/10.1016/j.jfluchem.2017.11.013
State	Published - Feb 2018

ASJC Scopus Subject Areas

Biochemistry
Environmental Chemistry
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

Keywords

Computational docking
Curcuminoid-BF adducts
Fluorinated CUR-pyrazoles and isoxazoles
Fluorocurcuminoids
X-ray analysis
in-vitro bioassay

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10.1016/j.jfluchem.2017.11.013

Cite this

Laali, K. K., Greves, W. J., Correa-Smits, S. J., Zwarycz, A. T., Bunge, S. D., Borosky, G. L., Manna, A., Paulus, A., & Chanan-Khan, A. (2018). Novel fluorinated curcuminoids and their pyrazole and isoxazole derivatives: Synthesis, structural studies, Computational/Docking and in-vitro bioassay. Journal of Fluorine Chemistry, 206, 82-98. https://doi.org/10.1016/j.jfluchem.2017.11.013

Laali, KK, Greves, WJ, Correa-Smits, SJ, Zwarycz, AT, Bunge, SD, Borosky, GL, Manna, A, Paulus, A & Chanan-Khan, A 2018, 'Novel fluorinated curcuminoids and their pyrazole and isoxazole derivatives: Synthesis, structural studies, Computational/Docking and in-vitro bioassay', Journal of Fluorine Chemistry, vol. 206, pp. 82-98. https://doi.org/10.1016/j.jfluchem.2017.11.013

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title = "Novel fluorinated curcuminoids and their pyrazole and isoxazole derivatives: Synthesis, structural studies, Computational/Docking and in-vitro bioassay",

keywords = "Computational docking, Curcuminoid-BF adducts, Fluorinated CUR-pyrazoles and isoxazoles, Fluorocurcuminoids, X-ray analysis, in-vitro bioassay",

author = "Laali, \{Kenneth K.\} and Greves, \{William J.\} and Correa-Smits, \{Sebastian J.\} and Zwarycz, \{Angela T.\} and Bunge, \{Scott D.\} and Borosky, \{Gabriela L.\} and Alak Manna and Aneel Paulus and Asher Chanan-Khan",

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year = "2018",

month = feb,

doi = "10.1016/j.jfluchem.2017.11.013",

language = "English",

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pages = "82--98",

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TY - JOUR

T1 - Novel fluorinated curcuminoids and their pyrazole and isoxazole derivatives

T2 - Synthesis, structural studies, Computational/Docking and in-vitro bioassay

AU - Laali, Kenneth K.

AU - Greves, William J.

AU - Correa-Smits, Sebastian J.

AU - Zwarycz, Angela T.

AU - Bunge, Scott D.

AU - Borosky, Gabriela L.

AU - Manna, Alak

AU - Paulus, Aneel

AU - Chanan-Khan, Asher

PY - 2018/2

Y1 - 2018/2

KW - Computational docking

KW - Curcuminoid-BF adducts

KW - Fluorinated CUR-pyrazoles and isoxazoles

KW - Fluorocurcuminoids

KW - X-ray analysis

KW - in-vitro bioassay

UR - https://www.scopus.com/pages/publications/85038823282

UR - https://www.scopus.com/pages/publications/85038823282#tab=citedBy

U2 - 10.1016/j.jfluchem.2017.11.013

DO - 10.1016/j.jfluchem.2017.11.013

M3 - Article

AN - SCOPUS:85038823282

SN - 0022-1139

VL - 206

SP - 82

EP - 98

JO - Journal of Fluorine Chemistry

JF - Journal of Fluorine Chemistry

ER -

Novel fluorinated curcuminoids and their pyrazole and isoxazole derivatives: Synthesis, structural studies, Computational/Docking and in-vitro bioassay

ASJC Scopus Subject Areas

Keywords

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