Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo

Zhongwei Liu; Neal Shah; Kent L. Marshall; Samuel A. Sprowls; Pushkar Saralkar; Afroz Mohammad; Kathryn E. Blethen; Tasneem A. Arsiwala; Ross Fladeland; Paul R. Lockman; Weimin Gao

doi:10.1007/s00204-021-03147-4

Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo

Zhongwei Liu
, Neal Shah
, Kent L. Marshall
, Samuel A. Sprowls
, Pushkar Saralkar
, Afroz Mohammad
, Kathryn E. Blethen
, Tasneem A. Arsiwala
, Ross Fladeland
, Paul R. Lockman
, Weimin Gao

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	3575-3587
Number of pages	13
Journal	Archives of Toxicology
Volume	95
Issue number	11
DOIs	https://doi.org/10.1007/s00204-021-03147-4
State	Published - Nov 2021
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus Subject Areas

Toxicology
Health, Toxicology and Mutagenesis

Keywords

ABT199
ABT263
Bcl-2 inhibitors
EGFR-TKIs
Synergism

Access to Document

10.1007/s00204-021-03147-4

Cite this

@article{a7468c1fb6a146e79acdaf8b1ac3bd5d,

title = "Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo",

keywords = "ABT199, ABT263, Bcl-2 inhibitors, EGFR-TKIs, Synergism",

author = "Zhongwei Liu and Neal Shah and Marshall, \{Kent L.\} and Sprowls, \{Samuel A.\} and Pushkar Saralkar and Afroz Mohammad and Blethen, \{Kathryn E.\} and Arsiwala, \{Tasneem A.\} and Ross Fladeland and Lockman, \{Paul R.\} and Weimin Gao",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.",

year = "2021",

month = nov,

doi = "10.1007/s00204-021-03147-4",

language = "English",

volume = "95",

pages = "3575--3587",

number = "11",

}

TY - JOUR

T1 - Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo

AU - Liu, Zhongwei

AU - Shah, Neal

AU - Marshall, Kent L.

AU - Sprowls, Samuel A.

AU - Saralkar, Pushkar

AU - Mohammad, Afroz

AU - Blethen, Kathryn E.

AU - Arsiwala, Tasneem A.

AU - Fladeland, Ross

AU - Lockman, Paul R.

AU - Gao, Weimin

PY - 2021/11

Y1 - 2021/11

KW - ABT199

KW - ABT263

KW - Bcl-2 inhibitors

KW - EGFR-TKIs

KW - Synergism

UR - https://www.scopus.com/pages/publications/85113790779

UR - https://www.scopus.com/pages/publications/85113790779#tab=citedBy

U2 - 10.1007/s00204-021-03147-4

DO - 10.1007/s00204-021-03147-4

M3 - Article

C2 - 34455456

AN - SCOPUS:85113790779

SN - 0340-5761

VL - 95

SP - 3575

EP - 3587

JO - Archives of Toxicology

JF - Archives of Toxicology

IS - 11

ER -

Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo

UN SDGs

ASJC Scopus Subject Areas

Keywords

Access to Document

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