Progressive Sub-MIC Exposure of Klebsiella pneumoniae 43816 to Cephalothin Induces the Evolution of Beta-Lactam Resistance without Acquisition of Beta-Lactamase Genes

Jasmine R. Anderson, Nghi B. Lam, Jazmyne L. Jackson, Sean M. Dorenkott, Taylor Ticer, Emir Maldosevic, Amanda Velez, Megan R. Camden, Terri N. Ellis

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number887
JournalAntibiotics
Volume12
Issue number5
DOIs
StatePublished - May 2023

ASJC Scopus Subject Areas

  • Microbiology
  • Biochemistry
  • General Pharmacology, Toxicology and Pharmaceutics
  • Microbiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)

Keywords

  • Klebsiella pneumoniae
  • antibiotic resistance
  • beta-lactams
  • capsule
  • selection window

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