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Stress-induced IL-6 response patterns amplify the link between daily negative affect and later depressive symptoms during bereavement

  • E. Lydia Wu-Chung
  • , Daniel L. Argueta
  • , Robert Suchting
  • , Ryan L. Brown
  • , Michelle A. Chen
  • , Angie S. LeRoy
  • , Kyle W. Murdock
  • , Cobi J. Heijnen
  • , Christopher P. Fagundes
  • Rice University
  • Texas Christian University
  • Pennsylvania State University

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number106774
Pages (from-to)106774
JournalBrain, Behavior, and Immunity
Volume136
Early online dateApr 20 2026
DOIs
StateE-pub ahead of print - Apr 20 2026

ASJC Scopus Subject Areas

  • Immunology
  • Endocrine and Autonomic Systems
  • Behavioral Neuroscience

Keywords

  • Daily negative affect
  • Depression
  • Depressive symptoms
  • Emotion
  • IL-6
  • Inflammation
  • Stress reactivity
  • Stressful life event
  • Trier Social Stress Test
  • Widowhood
  • Bereavement
  • Interleukin-6/blood
  • Humans
  • Middle Aged
  • Male
  • Widowhood/psychology
  • Stress, Psychological/blood
  • Female
  • Adult
  • Aged
  • Affect/physiology
  • Depression/blood

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