Synthesis, Computational Docking Study, and Biological Evaluation of a Library of Heterocyclic Curcuminoids with Remarkable Antitumor Activity

  • Kenneth K. Laali
  • , William J. Greves
  • , Angela T. Zwarycz
  • , Sebastian J. Correa Smits
  • , Frederick J. Troendle
  • , Gabriela L. Borosky
  • , Sharoon Akhtar
  • , Alak Manna
  • , Aneel Paulus
  • , Asher Chanan-Khan
  • , Manabu Nukaya
  • , Gregory D. Kennedy

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1895-1908
Number of pages14
JournalChemMedChem
Volume13
Issue number18
DOIs
StatePublished - Sep 19 2018

ASJC Scopus Subject Areas

  • Biochemistry
  • Molecular Medicine
  • Pharmacology
  • Drug Discovery
  • General Pharmacology, Toxicology and Pharmaceutics
  • Organic Chemistry

Keywords

  • antitumor agents
  • apoptosis
  • binding affinity
  • curcuminoids
  • multiple myeloma

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