Genome-wide analysis of denervation induced gene expression in mouse triceps surae muscle

  • David S. Waddell (Contributor)

Dataset

Description

Accession Number: GSE44205

Platform:
GPL6105: Illumina mouse-6 v1.1 expression beadchip

Organism: Mus musculus

Published on 2013-02-12

Summary:
Analysis of denervation induced regulation of muscle mass at gene expression level. The hypothesis tested in the present study was that the presence of MuRF1 contributes to the extent of gene expression changes observed in specific sets of genes during a challenge leading to muscle atrophy. Results provide important information on the response of triceps surae muscle to sciatic nerve resection (denervation), such as specific structural, metabolic, and neuromuscular junction associated genes, that may be influenced by MuRF1 during atrophy.

Overall Design:
Total RNA obtained from isolated triceps surae muscle subjected to 3 or 14 days post-denervation compared to nonsurgically treated littermate control muscles.

Contact:
Name: J. David Furlow
Organization: UC Davis
Address: One Shields Avenue Davis CA 95616 USA
Email: [email protected]

Organization: Illumina Inc.
Address: 9885 Towne Centre Drive San Diego CA 92121 USA
Email: [email protected], [email protected]
Phone: 1 800 809 4566
Web-Link: www.illumina.com
Datos disponiblesfeb 8 2013

Citar esto