Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy

Christina A. von Roemeling; Thomas R. Caulfield; Laura Marlow; Ilah Bok; Jiang Wen; James L. Miller; Robert Hughes; Lori Hazlehurst; Anthony B. Pinkerton; Derek C. Radisky; Han W. Tun; Yon Son Betty Kim; Amy L. Lane; John A. Copland

doi:10.18632/oncotarget.21545

Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy

Christina A. von Roemeling
, Thomas R. Caulfield
, Laura Marlow
, Ilah Bok
, Jiang Wen
, James L. Miller
, Robert Hughes
, Lori Hazlehurst
, Anthony B. Pinkerton
, Derek C. Radisky
, Han W. Tun
, Yon Son Betty Kim
, Amy L. Lane
, John A. Copland

Chemistry and Biochemistry

Producción científica: Article › revisión exhaustiva

Idioma original	English
Páginas (desde-hasta)	3-20
Número de páginas	18
Publicación	Oncotarget
Volumen	9
N.º	1
DOI	https://doi.org/10.18632/oncotarget.21545
Estado	Published - 2018

ASJC Scopus Subject Areas

Oncology

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10.18632/oncotarget.21545

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von Roemeling, C. A., Caulfield, T. R., Marlow, L., Bok, I., Wen, J., Miller, J. L., Hughes, R., Hazlehurst, L., Pinkerton, A. B., Radisky, D. C., Tun, H. W., Kim, Y. S. B., Lane, A. L., & Copland, J. A. (2018). Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy. Oncotarget, 9(1), 3-20. https://doi.org/10.18632/oncotarget.21545

von Roemeling, CA, Caulfield, TR, Marlow, L, Bok, I, Wen, J, Miller, JL, Hughes, R, Hazlehurst, L, Pinkerton, AB, Radisky, DC, Tun, HW, Kim, YSB, Lane, AL & Copland, JA 2018, 'Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy', Oncotarget, vol. 9, n.º 1, pp. 3-20. https://doi.org/10.18632/oncotarget.21545

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author = "\{von Roemeling\}, \{Christina A.\} and Caulfield, \{Thomas R.\} and Laura Marlow and Ilah Bok and Jiang Wen and Miller, \{James L.\} and Robert Hughes and Lori Hazlehurst and Pinkerton, \{Anthony B.\} and Radisky, \{Derek C.\} and Tun, \{Han W.\} and Kim, \{Yon Son Betty\} and Lane, \{Amy L.\} and Copland, \{John A.\}",

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AU - Caulfield, Thomas R.

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AU - Bok, Ilah

AU - Wen, Jiang

AU - Miller, James L.

AU - Hughes, Robert

AU - Hazlehurst, Lori

AU - Pinkerton, Anthony B.

AU - Radisky, Derek C.

AU - Tun, Han W.

AU - Kim, Yon Son Betty

AU - Lane, Amy L.

AU - Copland, John A.

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PY - 2018

Y1 - 2018

KW - Cancer

KW - Drug discovery

KW - High throughput drug screening

KW - Lipid metabolism

KW - Stearoyl CoA desaturase

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