Optimization of peptide hydroxamate inhibitors of insulin-degrading enzyme reveals marked substrate-selectivity

Samer O. Abdul-Hay; Amy L. Lane; Thomas R. Caulfield; Clémence Claussin; Juliette Bertrand; Amandine Masson; Shakeel Choudhry; Abdul H. Fauq; Guhlam M. Maharvi; Malcolm A. Leissring

doi:10.1021/jm301280p

Optimization of peptide hydroxamate inhibitors of insulin-degrading enzyme reveals marked substrate-selectivity

Samer O. Abdul-Hay, Amy L. Lane, Thomas R. Caulfield, Clémence Claussin, Juliette Bertrand, Amandine Masson, Shakeel Choudhry, Abdul H. Fauq, Guhlam M. Maharvi, Malcolm A. Leissring

Chemistry and Biochemistry

Producción científica: Article › revisión exhaustiva

Idioma original	English
Páginas (desde-hasta)	2246-2255
Número de páginas	10
Publicación	Journal of Medicinal Chemistry
Volumen	56
N.º	6
DOI	https://doi.org/10.1021/jm301280p
Estado	Published - mar 28 2013

ASJC Scopus Subject Areas

Molecular Medicine
Drug Discovery

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10.1021/jm301280p

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AU - Abdul-Hay, Samer O.

AU - Lane, Amy L.

AU - Caulfield, Thomas R.

AU - Claussin, Clémence

AU - Bertrand, Juliette

AU - Masson, Amandine

AU - Choudhry, Shakeel

AU - Fauq, Abdul H.

AU - Maharvi, Guhlam M.

AU - Leissring, Malcolm A.

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JO - Journal of Medicinal Chemistry

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