TY - JOUR
T1 - The effect of normally consumed amounts of sucrose or high fructose corn syrup on lipid profiles, body composition and related parameters in overweight/obese subjects
AU - Lowndes, Joshua
AU - Sinnett, Stephanie
AU - Pardo, Sabrina
AU - Nguyen, Von T.
AU - Melanson, Kathleen J.
AU - Yu, Zhiping
AU - Lowther, Britte E.
AU - Rippe, James M.
N1 - Lowndes, Sinnett, S., Pardo, S., Nguyen, V. T., Melanson, K. J., Yu, Z., Lowther, B. E., & Rippe, J. M. (2014). The Effect of Normally Consumed Amounts of Sucrose or High Fructose Corn Syrup on Lipid Profiles, Body Composition and Related Parameters in Overweight/Obese Subjects. Nutrients, 6(3), 1128–1144. https://doi.org/10.3390/nu6031128
PY - 2014/3/17
Y1 - 2014/3/17
N2 - The American Heart Association (AHA) has advocated that women and men not consume more than 100 and 150 kcal/day, respectively, from added sugars. These levels are currently exceeded by over 90% of the adult population in the United States. Few data exist on longer-term metabolic effects when sucrose and High Fructose Corn Syrup (HFCS), the principal sources of added dietary sugars, are consumed at levels typical of the general population. Sixty five overweight and obese individuals were placed on a eucaloric (weight stable) diet for 10-weeks, which incorporated sucrose- or HFCS-sweetened, low-fat milk at 10% or 20% of calories in a randomized, double-blinded study. All groups responded similarly (interaction p > 0.05). There was no change in body weight in any of the groups over the 10-week study, or in systolic or diastolic blood pressure. Likewise, there were no changes in total cholesterol, triglycerides, low-density lipoprotein (LDL), or apolipoprotein B (Apo B). We conclude that (1) when consumed as part of a eucaloric diet fructose-when given with glucose (as normally consumed) does not promote weight gain or an atherogenic lipid profile even when consumed at two to four times the level recently recommended by the AHA. (2) There were no differences between HFCS and sucrose on these parameters. © 2014 by the authors; licensee MDPI, Basel, Switzerland.
AB - The American Heart Association (AHA) has advocated that women and men not consume more than 100 and 150 kcal/day, respectively, from added sugars. These levels are currently exceeded by over 90% of the adult population in the United States. Few data exist on longer-term metabolic effects when sucrose and High Fructose Corn Syrup (HFCS), the principal sources of added dietary sugars, are consumed at levels typical of the general population. Sixty five overweight and obese individuals were placed on a eucaloric (weight stable) diet for 10-weeks, which incorporated sucrose- or HFCS-sweetened, low-fat milk at 10% or 20% of calories in a randomized, double-blinded study. All groups responded similarly (interaction p > 0.05). There was no change in body weight in any of the groups over the 10-week study, or in systolic or diastolic blood pressure. Likewise, there were no changes in total cholesterol, triglycerides, low-density lipoprotein (LDL), or apolipoprotein B (Apo B). We conclude that (1) when consumed as part of a eucaloric diet fructose-when given with glucose (as normally consumed) does not promote weight gain or an atherogenic lipid profile even when consumed at two to four times the level recently recommended by the AHA. (2) There were no differences between HFCS and sucrose on these parameters. © 2014 by the authors; licensee MDPI, Basel, Switzerland.
KW - Body mass; High fructose corn syrup; Sucrose
UR - https://doi.org/10.3390/nu6031128
U2 - 10.3390/nu6031128
DO - 10.3390/nu6031128
M3 - Article
SN - 2072-6643
VL - 6
SP - 1128
EP - 1144
JO - Nutrients
JF - Nutrients
IS - 3
ER -